PEG 3350 Laxative: What It Is, How It Works, and What Alternatives Exist

When you’re dealing with stubborn constipation, PEG 3350 laxative, a non-absorbable osmotic agent used to draw water into the colon and soften stool. Also known as polyethylene glycol 3350, it’s one of the most trusted names in over-the-counter relief—found in brands like MiraLAX and generic versions sold worldwide. Unlike stimulant laxatives that force contractions, PEG 3350 works quietly by holding water in the stool, making it easier to pass without cramping or urgency. It’s not a quick fix, but it’s reliable, safe for daily use, and often recommended by doctors for chronic issues or before medical procedures.

PEG 3350 doesn’t get absorbed by your body. Instead, it sits in your intestines like a sponge, pulling in just enough fluid to make stools soft and bulky enough to move naturally. That’s why it’s also used for bowel prep, the process of clearing the colon before a colonoscopy or surgery. People often mix it with water or flavored drinks to make it easier to swallow. Unlike some harsher laxatives, it rarely causes electrolyte imbalances or dependence, which is why it’s a top pick for seniors, kids, and long-term users. It’s also the go-to for people who need regular relief without the jittery side effects of stimulants like senna or bisacodyl.

But PEG 3350 isn’t the only option. If you’ve tried it and still feel stuck, you might be looking at other osmotic laxatives, substances that work similarly by drawing water into the gut like magnesium hydroxide or lactulose. Or maybe you’re wondering if fiber supplements, probiotics, or even hydration tweaks could help more. Some people find that combining PEG 3350 with gentle movement or abdominal massage makes a noticeable difference. Others switch to stool softeners like docusate when they need something milder. The key is knowing what’s causing your constipation—dehydration, slow motility, medication side effects, or something deeper—and matching the tool to the problem.

You’ll find plenty of real-world experiences in the posts below—people who’ve used PEG 3350 for years, those who switched after side effects, and others who found better results with diet changes or alternative treatments. Whether you’re just starting out or you’ve been through a dozen brands, there’s something here that speaks to your situation. No fluff. No guesswork. Just clear, practical info on what works, what doesn’t, and what to try next.