When you have nasal polyps and asthma, a pair of chronic conditions where swollen tissue blocks the nose and airways tighten, making breathing difficult. These two don’t just happen at the same time—they feed off each other. People with nasal polyps are far more likely to have severe asthma, and those with stubborn asthma often develop polyps over time. It’s not coincidence. It’s inflammation—the same kind that turns your sinuses into swollen lumps and your lungs into tight, sensitive tubes.
This shared inflammation is driven by immune signals like IgE and IL-5. That’s why anti-IgE, a type of targeted biologic treatment that blocks the allergy-triggering antibody and anti-IL-5, a therapy that shuts down a key inflammatory cell linked to both polyps and asthma work so well for people with both conditions. These aren’t just asthma drugs—they’re polyp reducers too. Studies show patients on these treatments shrink polyps, need fewer steroids, and breathe easier through their nose and lungs at the same time. It’s one treatment, two problems solved.
Most people think nasal congestion is just a cold or allergies. But if you’ve had it for months, struggle to breathe through your nose, and also wheeze or feel tight in your chest, you’re likely dealing with a deeper link. Steroid sprays help, but they often aren’t enough. Oral steroids give relief but come with side effects if used long-term. That’s where biologics step in—not as a last resort, but as a smarter option for those stuck in a cycle of worsening symptoms. You don’t have to choose between treating your nose or your lungs anymore.
What you’ll find here are real, practical insights into how these conditions interact, what medications actually work, and how to break the cycle before it leads to surgery or hospital visits. From how humidity affects your meds to why some people respond better to certain biologics, this collection cuts through the noise and gives you what matters: clear, science-backed ways to take control.
Aspirin-exacerbated respiratory disease (AERD) causes severe asthma and nasal polyps in adults who react to NSAIDs like aspirin and ibuprofen. Learn the signs, why it's often missed, and how aspirin desensitization can change your life.